Czech and Slovak Ophthalmology 451 Original article About Cryptophthalmos (2nd Czech Study) Krásný Jan https://orcid.org/0000-0002-0341-0094 Čakrtová Marie Kletenský Jiří Novák Vítězslav Šach Josef https://orcid.org/0000-0001-9287-7915 10 11 2015 6 2

Aim: To get acquainted with the 2nd Czech study about cryptophthamos and with self-surgical methods. Material: The boy with unilateral complete cryptophthalmos of left eye was treated from 2 to 20 years. The girls was treated from 4 month to 5 year yet for right abortive cryptophthalmos with microblepharon and left complete type still waiting for solutions. Surgical methods and results: Authors present a surgical procedures for correction of the upper and lower eyelids and ocular anomalies both patients studied. Successful reconstruction of palpebral fissure took place in several stages at the boy. The surgical procedure gradually contained: the insertion of gradually increased convex concave circular-shaped implant (silicone ruber) due a modeling of palpebral fissure, an enucleation of rudimentary eye, a reconstruction of bottom palpebral fissure by retro-auricular skin graf and a releasing of the lower transitory fold by the cul-de-sac method. An adequate depth of palpebral fissure to allow perfect position of an aesthetic protesis. Enucleated eye was atypically shaped, remiding partly sand-glass clock. The cornea was replaced by thick fibrous membrane, the iris and the lens were not revealed. Gliomatic retina was detached nearly totaly and the optic nerv was rudimental. The repairing the upper lid coloboma of girl by a lid rotation flap reconstruction using the inferior eyelid was performed at the age 17 month. Corneal dermoid simultaneously removed (histologically verified). Upper conjunctival fornix was formed using the spherical covering foil (silicone rubber) before and after the reconstruction of the lid. Conclusions: Plastic reconstructions required the need for patient access without trying immediate effect. An important role played silicone rubber implants (elastomer medical grade) which used temporarily.

 cryptophthalmos microblepharon relief surgery silicon ruber implants References Apple, D.J., Rabb, M.F.: Ocular Pathology, 5th edition., Mosby, 1998 , St. Louis, p.16. Barishak, Y.R .: Embryology of the Eye and Its Adnexa. Karger, Basel, 2001, p.132. Barisic, I., Odek, L., et al.: Fraser Syndrome: Epidemiologic Study in a European Population. Am J Med Genet A, 30; 2013: 1012–1018. Berg, C., Geipel, A., et al.: Prenatal Detection of Fraser Syndrome without Cryptophthalmos. Case Report and Review of Literature. Ultrasound Obstet Gynecol, 18; 2001: 76–80. Brazier, D.J., Hardman–Lea, S.J., Collins, J.R .: Cryphtophthalmos: Surgical Treatment of the Congenital Symblepharon Variant Brit J Ophthalmol, 70; 1986: 391–395. Celebi, A.R., Sasani, H.: Differentiation ger, New York, 2003, p.1038 . Conlon, R.M., Sutula, F.C.: Congenital Eyelid Anomalies. In Albert, D.M. & Jakobiec, F.A.: Principles and Practice of Ophthalmology, Vol. III., W.B. Saunders Co. Philadelphia, 1994, p. 1693–1699. Dibben, K., Rabinowitz, Y.S. et al.: Surgical Correction of Incomplete Crytophthalmos in Fraser Syndrome. Am J Ophthalmol, 124; 1997: 107–109. Duke-Elder, S.: Congenital Anomalies of the Ocular Adnexa. In System of Ophthalmology, Vol. III. Congenital Deformities, H. Kimptom, London, 1964, pp. 827–835. Eibschitz-T simhoni, M.: Ocular Manifestation of Inherited Diseases. In Wright, K.W., Spiegel, P.H.: Pediatric Ophthalmology and Strabismus. Spri- Francois, J.: Syndrome malformatif avec cryptophthalme. Ophthalmologica, Basel, 150, 1965: 215. Fryns, J.P ., van Schoubroeck, D., et al.: Diagnostic Echographic Findings in Cryptophthalmos Syndrome (Fraser Syndrome). Prenat. Diagn., 17, 1997: 582–584. Fuchs, H.E., Duan, A.: Text-book of Ophthalmology. J. B. Lippincott Co., Philadelphia 1923, p. 437. Gerinec, A.: Detská oftalmológia, Osveta, Martin, 2005, s. 104. Goldhammer, Y., Smith, J.L.: Cryptophthalmos Syndrome with Basal Encephaloceles. Am J Ophthalmol, 80; 1975: 146–149. Hambire, S.D ., Bhavsar, PP., Jayakar, A.V.: Fraser-Cryptophthalmos Syndrome with Cardiovascular Malformations: stranného kryptoftalmu. Folia Strabol Neuroophthalmol; 14, 2014, suppl. I.: 39–43. Chalupecký, J.: Oční lékařství. Hejda a Tucek, Praha, 1902, s. 316 Krásný, J.: Plastika anoftalmického spojivkového vaku upravenou metodikou cul-de-sac. Čes a Slov Oftal, 71; 2015: 37–43. Krásny, J. Autrata, R.: Pedooftalmologie a strabismus. In Kuchynka, P. a kol.: Oční lékařství, Grada, Praha, 2007, s. 647, 653. 20. Krásný, J., Čakrtová, M., Novák, V.: Jednostranný kryptoftalmus–plastická úprava. Folia Strabol Neuroophthalmol; 10, 2009, suppl. I.: 86– 88. Krásný, J., Kletenský, J.: Kombinace pravostranného horního mikroblefaronu s kongenitálním symblefaronem a levo- Case of Incomplete Cryptophthalmos. Adv Ophthalmic Plast Reconstr Surg, 9; 1992: 81–91. Krásný, J., Novák, V.: Anophthalmus– spojivkový implantát. Čes a Slov Oftal, 59; 2003: 33–39. Krásný, J., Novák, V.: Kulová krycí folie– silikonový implantát formující přechodné řasy spojivky. Čes a Slov Oftal, 63; 2007: 369–372. Nouby,G.: Congenital Upper Eyelid Coloboma and Cryptophthalmos. Ophthal. Plast Reconstr Surg, 18, 2902: 373–377. Mann, I.: Development Abnormalities of the Eye. H. Kimptom, London,1957, p.371. Morax, S., Herdan, M.L., Hurbli, T.: Orbito-palpebral Reconstruction in Two A Rare Association. Indian. Pediatr, 40; 2003: 888–900. Murthy, R., Gupta H.: Novel Surgical Techniqe for Management of Partial Cryptophthalmos. Indian J Ophthalmol, 62; 2014: 1096–1098. Neuhas, R.W., Hawes, M.J.: Inadequate Inferior Cul-de-sac in the Anophthalmic Soket. Ophtalmology, 99; 1992: 153– Otradovec, J., Janovský, M.: O krytoftalmu. Čs Oftal, 18; 1962: 128–138. Oztoprak, I., Erdogan, H., et al.: A Case Scizencephaly Presenting with Unilateral Cryptophthalmos. Br. J. Radiol., 2008, doi: 10.1259/bjr/56258419.10.1259/bjr/56258419 Saleh, G.M., Hussain, B., et al.: A Sur-