<?xml version="1.0" encoding="UTF-8"?>
<article article-type="research-article" dtd-version="1.3" xml:lang="en">
  <front>
    <journal-meta>
      <journal-title-group>
        <journal-title>Czech and Slovak Ophthalmology</journal-title>
      </journal-title-group>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">54</article-id>
      <article-categories>
        <subj-group>
          <subject>Case report</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Bilateral Macular Edema on a Background of Optic Disc Drusen</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Štrofová</surname>
            <given-names>Helena</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Jarošová</surname>
            <given-names>Alena</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Ženíšková</surname>
            <given-names>Renata</given-names>
          </name>
        </contrib>
      </contrib-group>
      <pub-date date-type="pub" publication-format="electronic">
        <day>30</day>
        <month>1</month>
        <year>2016</year>
      </pub-date>
      <issue>1</issue>
      <elocation-id>7</elocation-id>
      <abstract>
        <p>In the case report, bilateral cystoid macular edema with optic disc edema on the left side in young man is described. As etiology out of the systemic diseases, we considered the hypertension. The results of the neurological examination, including the brain CT examination were physiological. The patient was examined by the internal specialist, the hypertension was treated – and it was the presumed etiology of the ophthalmologic findings. Due to the repeated worsening of the ophthalmologic findings, we searched for other etiology. Bilateral buried optic disc drusen were found by means of ultrasound. Bilateral cystoid macular edema and optic disc edema were evaluated as signs of circulatory disturbance of the posterior ciliary arteries and macular choroid caused by optic disc drusen. The antiglaucomatic treatment was started with – alpha 2 adrenergic receptors agonist – brimonidine – which increases the blood supply of the optic nerve and decreases the intraocular pressure with presumed delay of axons dysfunction.</p>
      </abstract>
      <kwd-group>
        <kwd>macular edema</kwd>
        <kwd>optic disc drusen</kwd>
        <kwd>intraocular pressure</kwd>
        <kwd>visual field</kwd>
        <kwd>ultrasound</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <back>
    <ref-list>
      <title>References</title>
      <ref id="R9095">
        <mixed-citation>Aumiller, M. S.: Optic disc drusen: Complications and management. Optometry – Journal of the American Optometric Association. January 2007, vol. 78, no. 1, 10–16.</mixed-citation>
      </ref>
      <ref id="R9096">
        <mixed-citation>Auw-Haedrich, C., Staubach, F. Witschel, H.: Optic Disk Drusen. Survey of</mixed-citation>
      </ref>
      <ref id="R9097">
        <mixed-citation>Baget-Bernaldiz, M., Soler, L. N., Romero-Aroca, P.: Optical coherence tomography study in tamoxifen maculopathy. Archivos de la Sociedad Española de Oftalmología [online]. 2008, vol. 83, iss.</mixed-citation>
      </ref>
      <ref id="R9098">
        <mixed-citation>Baráková, D.: Echografie v oftalmologii.</mixed-citation>
      </ref>
      <ref id="R9099">
        <mixed-citation>Davis, P. L., Jay, W. M.: Optic nerve head drusen. Seminars in Ophthalmology, ních 37 operovaných očí. Čes a slov Oftalmol, 1996, vol. 52, no. 5: 297–308.</mixed-citation>
      </ref>
      <ref id="R9100">
        <mixed-citation>Grippo, T. M., Rogers, S. W., Tsai, J. C., et al.: Optic Disc Drusen: Practical implications and management. Glaucoma today, January – February 2012: 19–24.</mixed-citation>
      </ref>
      <ref id="R9101">
        <mixed-citation>Hauptvogelová, M. – Šustykevičová, Z.: Non-arteritická predná ischemická optická neuropatia pri drúzach zrakového nervu. Česká a slovenská oftalmologie, 2010, vol. 66, no. 2, s. 184–187.</mixed-citation>
      </ref>
      <ref id="R9102">
        <mixed-citation>Jirásková, N., Rozsíval, P.: Dekomprese obalu zrakového nervu. Česká a slovenská oftalmologie, 1995, vol. 51, 254– 257.</mixed-citation>
      </ref>
      <ref id="R9103">
        <mixed-citation>Jirásková, N., Rozsíval, P.: Dekomprese obalu zrakového nervu – výsledky u prv-</mixed-citation>
      </ref>
      <ref id="R9104">
        <mixed-citation>Jirásková, N., Rozsíval, P.: Výsledky 62 dekompresí obalu zrakového nervu. Čes a slov Oftalmol, 1999; vol. 55, no. 3: 136–144.</mixed-citation>
      </ref>
      <ref id="R9105">
        <mixed-citation>Kanski, J. J.: Ophtalmology: Clinical Signs ad Differential Diagnosis. 5th edition. Mosby International Limited, 2007. 485 s. ISBN 0-7234-3121-3.</mixed-citation>
      </ref>
      <ref id="R9106">
        <mixed-citation>Kuchynka, P., et al.: Oční lékařství. 1.vyd. Praha: Grada, 2007. 768 s. ISBN 978-80-247-1163–8.</mixed-citation>
      </ref>
      <ref id="R9107">
        <mixed-citation>Matušková, V., Vysloužilová, D.: Možnost léčby oboustranného makulárního edému bez anti VEGF léčby. Čes a slov Oftalmol, 2010; vol. 66, no. 1: 30–35. December 2003; vol. 18, no. 4: 222– 242.</mixed-citation>
      </ref>
      <ref id="R9108">
        <mixed-citation>Studička, J.: Indikace Avastinu v oftalmologii. Čes a slov Oftalmol, 2010; vol. 66, no. 5: 229–233.</mixed-citation>
      </ref>
      <ref id="R9109">
        <mixed-citation>Suelves, A. M., Francés-Munoz, E., Gallego-Pinazo, R., et al.: Central serous papillopathy by optic nerve head drusen. Clinical Ophthalmology, November 2010; vol. 25, no. 4: 1379–1382.</mixed-citation>
      </ref>
      <ref id="R9110">
        <mixed-citation>Tan, C. S., Teoh, S. C., CHan, D. P. , et al.: Dengue retinopathy manifesting with bilateral vasculitis and macular oedema. Eye, June 2007; vol. 21, no. 6: 875–877.</mixed-citation>
      </ref>
      <ref id="R9111">
        <mixed-citation>Tryfon, G. R., Marilita, M. M.: Cystoid macular edema. Clinical Ophthalmology, December 2008; vol. 2, no. 4: 919–</mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>
