Czech and Slovak Ophthalmology 552 Original article Clinical Variability of Best’s Disease Streicher Teodor Špirková Jana Tichá Marie 22 10 2012 5 3

Retrospective view of the various phenotypes 20 persons affected by classic solitary form of vitelliform macular dystrophy, in 3 pedigrees with autosomal dominant transmission and in 4 single cases. Long-term monitoring allows to observe the variability of expression, from classic course to peculiarity of the clinical expression in the disc development and their corresponding functions of the central retina.

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